Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338529 | 0.93 | LPAR1 (0.44) | ALDH1A1LPAR1MAPTKDM4EHTT | |
| SCHEMBL2337280 | 0.92 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1HPGDLPAR1MAPT | |
| SCHEMBL3705980 | 0.90 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1LPAR1MAPTKDM4E | |
| SCHEMBL2335059 | 0.89 | LPAR1 (0.41) | ALDH1A1MAPK1L3MBTL1LPAR1MAPT | |
| SCHEMBL2337994 | 0.87 | HDAC6 (0.43) | MAPTSYK | |
| SCHEMBL2334158 | 0.84 | SMN1; SMN2 (0.40) | MAPK1L3MBTL1LPAR1MAPTSMN1; SMN2 | |
| SCHEMBL2335503 | 0.84 | LPAR1 (0.44) | ALDH1A1HPGDLPAR1MAPTKDM4E | |
| SCHEMBL2635955 | 0.83 | ABCC3 (0.39) | LPAR1TDP1LMNACACNA1FABCB1 | |
| SCHEMBL2336265 | 0.83 | LPAR1 (0.41) | ALDH1A1L3MBTL1HPGDLPAR1MAPT | |
| SCHEMBL3706822 | 0.83 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1LPAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |