Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23365148 | 0.81 | MGLL (0.47) | ALDH1A1CCR3ENPP2MGLLADRA1D | |
| SCHEMBL22265924 | 0.81 | GBA1 (0.45) | NOS3NOS1NOS2HRH3ENPP2 | |
| SCHEMBL22265663 | 0.77 | STS (0.53) | KDM4EENPP2MGLL | |
| SCHEMBL27741252 | 0.77 | HRH3 (0.54) | HRH3CCR3HTR6 | |
| SCHEMBL22265854 | 0.74 | USP30 (0.43) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL22278142 | 0.73 | ALDH1A1 (0.62) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL2056158 | 0.72 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CCR3 | |
| SCHEMBL22278140 | 0.70 | CHKA (0.44) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL22278130 | 0.70 | CHKA (0.42) | NOS3NOS1NOS2HRH3KDM4E | |
| SCHEMBL13226822 | 0.69 | CYP2A6 (0.48) | ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021097240-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2021-05-20 | — | — | WO | disclosed |