Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22278130 | 0.83 | CHKA (0.42) | CHKANOS3NOS1NOS2NR1D2 | |
| SCHEMBL13346871 | 0.82 | NR1D2 (0.45) | NR1D2ALDH1A1FPR2PROKR1 | |
| SCHEMBL15965585 | 0.80 | NR1D2 (0.44) | NR1D2FPR2PROKR1 | |
| SCHEMBL22278127 | 0.78 | PROKR1 (0.47) | NR1D2ALDH1A1FPR2PROKR1 | |
| SCHEMBL1911884 | 0.77 | PROKR1 (0.46) | NR1D2FPR2PROKR1 | |
| SCHEMBL27741252 | 0.76 | HRH3 (0.54) | — | |
| SCHEMBL31200218 | 0.76 | DPP4 (0.44) | DPP4DPP8 | |
| SCHEMBL5109838 | 0.75 | QDPR (0.50) | NOS3NOS1NOS2PLA2G7 | |
| SCHEMBL31200129 | 0.75 | DPP4 (0.39) | DPP4DPP8ALDH1A1 | |
| SCHEMBL8302415 | 0.74 | OPRM1 (0.51) | NR1D2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154571-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-07-30 | — | — | WO | disclosed |