Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21309845 | 1.00 | MME (0.40) | MMETGFBR1CA1CA2SMN1; SMN2 | |
| SCHEMBL23374703 | 1.00 | MME (0.40) | MMETGFBR1CA1CA2SMN1; SMN2 | |
| SCHEMBL28004382 | 0.84 | TGFBR1 (0.34) | MMETGFBR1MGAMGAASI | |
| SCHEMBL21261739 | 0.84 | CAD (0.42) | TGFBR1CYP2C9ALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL7921333 | 0.84 | CA1 (0.42) | CA1CA2SMN1; SMN2POLBZDHHC7 | |
| SCHEMBL8245351 | 0.84 | TGFBR1 (0.41) | MMETGFBR1CA1CA2SMN1; SMN2 | |
| SCHEMBL10296136 | 0.84 | CA1 (0.42) | CA1CA2SMN1; SMN2POLBZDHHC7 | |
| SCHEMBL14872113 | 0.80 | MME (0.39) | MMETGFBR1CA1CA2SMN1; SMN2 | |
| SCHEMBL23374708 | 0.80 | CA1 (0.35) | MMECA1CA2SMN1; SMN2CYP2C9 | |
| SCHEMBL21548093 | 0.79 | ITGA4 (0.36) | TGFBR1CA1CA2CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021093817-A1 | IMMUNOMODULATORY COMPOUNDS, COMPOSITION AND APPLICATION THEREOF | 杭州和正医药有限公司 | 2021-05-20 | — | — | WO | disclosed |