SCHEMBL2337533

SCHEMBL2337533

C1=Cc2c(ccc3ccccc23)ON1.C1=Cc2ccccc2ON1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
APP P05067 1/20 0.32
P2RX4 Q99571 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141092 0.91 CA12 (0.47) CA12CA9ALDH1A1KDM4EMEN1
SCHEMBL16341187 0.80 MAPT (0.37) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL8924 0.80 MAPT (0.37) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL3662203 0.80 MAPT (0.37) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL29804885 0.80 MAPT (0.37) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL28937998 0.79 CA12 (0.39) CA12CA9ALDH1A1KDM4EMEN1
Indole SCHEMBL29065921 0.78 TRPA1 (0.47) CA12CA9ALDH1A1KDM4EMEN1
SCHEMBL7679307 0.78 MAPT (0.36) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL7679297 0.78 MAPT (0.36) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL3201327 0.78 MAPT (0.36) ALDH1A1KDM4EMEN1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2055706-B1 Electrode and electrolyte membrane for fuel cell including a naphthoxazine based polymer and fuel cell using the electrode SAMSUNG ELECTRONICS LTD (KR) 2011-08-24 EP disclosed
US-5434043-A Photothermographic element with pre-formed iridium-doped silver halide grains MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-07-18 US disclosed