SCHEMBL141092

SCHEMBL141092

C1=Cc2c(ccc3ccccc23)ON1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 4/20 0.41
HPGD P15428 3/20 0.41
GAA P10253 3/20 0.41
MAPT P10636 3/20 0.41
GLA P06280 2/20 0.41
NPC1 O15118 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD17B10 Q99714 4/20 0.39
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPRT1 P00492 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2337533 0.91 CA12 (0.41) CA12CA9ALDH1A1KDM4EHPGD
SCHEMBL28937998 0.88 CA12 (0.39) CA12CA9ALDH1A1KDM4EHPGD
Indole SCHEMBL29065921 0.87 TRPA1 (0.47) CA12CA9ALDH1A1KDM4EHPGD
Pyrazole SCHEMBL10591536 0.85 CA12 (0.38) CA12CA9ALDH1A1KDM4EHPGD
SCHEMBL975005 0.84 ALDH1A1 (0.35) CA12CA9ALDH1A1KDM4EHPGD
Oxazolidine SCHEMBL10706621 0.84 CA12 (0.37) CA12CA9ALDH1A1KDM4EHPGD
Indoline SCHEMBL3956344 0.82 CA12 (0.35) CA12CA9ALDH1A1KDM4EHPGD
SCHEMBL29042071 0.82 CA12 (0.35) CA12CA9ALDH1A1KDM4EHPGD
SCHEMBL30785188 0.70 ALDH1A1 (0.39) CA12CA9ALDH1A1KDM4EHPGD
SCHEMBL3082146 0.69 CA12 (0.39) CA12CA9ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3127 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4304842-B1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC (CH) 2026-05-06 EP claimed
US-12285922-B2 Method for making photofunctional contact lenses ALCON INC. (CH) 2025-04-29 US claimed
US-12247169-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2025-03-11 US claimed
EP-4514597-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
CN-119487450-A Photoinitiator, composition and method for forming object 二次3D股份有限公司 2025-02-18 CN claimed
EP-4313567-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2025-01-29 EP claimed
EP-4237232-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-11-27 EP claimed
US-20240343698-A1 Bioderived monomers for the generation of polybenzoxazine thermosets and thermoplastics Alliance for Energy Innovation, LLC 2024-10-17 US claimed
US-12111443-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-10-08 US claimed
US-20240287379-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2024-08-29 US claimed
WO-1996034735-A1 ADHESIVE PHOTOCHROMIC MATRIX LAYERS FOR USE IN OPTICAL ARTICLES INNOTECH, INC. (US) 1996-11-07 WO claimed
WO-1996011926-A1 PHOTOCHROMIC NAPHTHOXAZINE COMPOUNDS PPG INDUSTRIES, INC. (US) 1996-04-25 WO claimed
CN-1120335-A Photochromic naphthopyran compounds PILKINGTON PLC (GB) 1996-04-10 CN claimed
WO-1996004576-A1 NOVEL SUBSTITUTED PHENANTHROPYRANS PPG INDUSTRIES, INC. (US) 1996-02-15 WO claimed
US-5405958-A Photochromic spiro(indoline)naphthoxazine compounds TRANSITIONS OPTICAL, INC. (US) 1995-04-11 US claimed
EP-0339661-B1 Photochromic substances RODENSTOCK OPTIK G (DE) 1994-04-20 EP claimed
EP-0390869-A4 ORGANIC PHOTOCHROMIC PIGMENT 1990-11-07 EP claimed
EP-0390869-A1 ORGANIC PHOTOCHROMIC PIGMENT PPG INDUSTRIES, INC. (US) 1990-10-10 EP claimed
US-4959471-A IMPROVED MIGRATION PROPERTIES IN PLASTICS, LENSES OPTISCHE WERKE G. RODENSTOCK (DE) 1990-09-25 US claimed
WO-1989005464-A1 ORGANIC PHOTOCHROMIC PIGMENT PPG INDUSTRIES, INC. (US) 1989-06-15 WO claimed