Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 14/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2328859 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1HPGD | |
| SCHEMBL660719 | 0.74 | RBP4 (0.42) | RBP4KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL2337563 | 0.71 | RBP4 (0.45) | RBP4KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL14236753 | 0.70 | TACR1 (0.38) | HPGD | |
| SCHEMBL16059034 | 0.69 | PRMT5 (0.47) | ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL15719231 | 0.68 | TACR1 (0.45) | HPGD | |
| SCHEMBL15720072 | 0.68 | SMN1; SMN2 (0.46) | ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL3209304 | 0.67 | FAAH (0.55) | GAA | |
| SCHEMBL7569154 | 0.66 | TP53 (0.56) | RBP4GAAKMT2ATDP1HTR2C | |
| SCHEMBL31147241 | 0.66 | TP53 (0.56) | RBP4GAAKMT2ATDP1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011100373-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-08-18 | — | — | WO | disclosed |