Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 15/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660719 | 0.75 | RBP4 (0.42) | RBP4ALDH1A1PROKR1KDM4EHPGD | |
| SCHEMBL2337559 | 0.71 | RBP4 (0.46) | RBP4ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL31613472 | 0.70 | RBP4 (0.73) | RBP4CYP2C19 | |
| SCHEMBL16059035 | 0.70 | SLC18A3 (0.47) | — | |
| SCHEMBL15719233 | 0.68 | SLC18A3 (0.46) | ALDH1A1KDM4E | |
| SCHEMBL15720074 | 0.68 | DRD2 (0.45) | — | |
| SCHEMBL20913744 | 0.68 | BRD4 (0.38) | KDM4E | |
| SCHEMBL24877818 | 0.67 | HTR2C (0.51) | RBP4PROKR1TDP1 | |
| SCHEMBL31487378 | 0.66 | RBP4 (0.63) | RBP4CYP2C19 | |
| SCHEMBL7569154 | 0.66 | TP53 (0.56) | RBP4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011100373-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-08-18 | — | — | WO | disclosed |