Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21446194 | 0.96 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1ALKIDO1KDM4E | |
| SCHEMBL26060295 | 0.95 | PLA2G2A (0.33) | HSP90AA1HSP90AB1ALKPLA2G2APLA2G4A | |
| SCHEMBL26060303 | 0.95 | PLA2G2A (0.33) | HSP90AA1HSP90AB1ALKPLA2G2APLA2G4A | |
| SCHEMBL26060274 | 0.95 | PLA2G2A (0.35) | HSP90AA1HSP90AB1ALKIDO1KDM4E | |
| SCHEMBL26060294 | 0.95 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1ALKIDO1KDM4E | |
| SCHEMBL26060301 | 0.95 | PLA2G2A (0.35) | HSP90AA1HSP90AB1ALKIDO1KDM4E | |
| SCHEMBL26060292 | 0.94 | PLA2G2A (0.33) | HSP90AA1HSP90AB1ALKIDO1PLA2G2A | |
| SCHEMBL26060278 | 0.94 | PLA2G2A (0.33) | HSP90AA1HSP90AB1ALKIDO1PLA2G2A | |
| SCHEMBL23376381 | 0.94 | HCRTR1 (0.32) | ALKMEN1MAPTKMT2APGR | |
| SCHEMBL23376065 | 0.94 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1ALKIDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147375-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147375-A1 | MATERIALS FOR ELECTRONIC DEVICES | PNMT, EFNA1, TES | HSP90AA1 4189/4885HSP90AB1 4705/4885ALK 1411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.