Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3190550 | 0.77 | CSNK1A1 (0.47) | CSNK1A1CLK4ALDH1A1KMT2ANOS3 | |
| SCHEMBL2339904 | 0.76 | CSNK1A1 (0.46) | CSNK1A1CLK4ALDH1A1KMT2ANOS3 | |
| SCHEMBL20489454 | 0.74 | HTT (0.44) | CSNK1A1CLK4ALDH1A1KMT2ANOS3 | |
| SCHEMBL10690802 | 0.74 | KDM4E (0.44) | CSNK1A1CLK4ALDH1A1KMT2ANOS3 | |
| SCHEMBL12528204 | 0.73 | NOS3 (0.32) | NOS3NOS1NOS2CCNA2CDK2 | |
| SCHEMBL12528297 | 0.73 | HTT (0.36) | ALDH1A1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL24774054 | 0.69 | CSNK1A1 (0.52) | CSNK1A1CLK4ALDH1A1KMT2AKDM4E | |
| SCHEMBL10261073 | 0.67 | CSNK1A1 (0.38) | CSNK1A1CLK4ALDH1A1KMT2ANOS3 | |
| SCHEMBL19009020 | 0.65 | TSHR (0.39) | CSNK1A1CLK4ALDH1A1KMT2AKDM4E | |
| SCHEMBL11666510 | 0.65 | CSNK1A1 (0.50) | CSNK1A1CLK4ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |