Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3190550 | 0.85 | CSNK1A1 (0.47) | CSNK1A1CLK4NOS3NOS2NOS1 | |
| SCHEMBL10690802 | 0.82 | KDM4E (0.44) | CSNK1A1CLK4NOS3NOS2NOS1 | |
| SCHEMBL20489454 | 0.82 | HTT (0.44) | CSNK1A1CLK4NOS3NOS2NOS1 | |
| SCHEMBL11666510 | 0.80 | CSNK1A1 (0.50) | CSNK1A1CLK4KDM4EHTTL3MBTL1 | |
| SCHEMBL24774054 | 0.76 | CSNK1A1 (0.52) | CSNK1A1CLK4KDM4EHTTL3MBTL1 | |
| SCHEMBL31539843 | 0.76 | MBOAT4 (0.44) | CSNK1A1CLK4KDM4EHTTL3MBTL1 | |
| SCHEMBL31539784 | 0.76 | MBOAT4 (0.44) | CSNK1A1CLK4KDM4EHTTL3MBTL1 | |
| SCHEMBL2337644 | 0.76 | CSNK1A1 (0.40) | CSNK1A1CLK4NOS3NOS2NOS1 | |
| SCHEMBL3190367 | 0.75 | NOS3 (0.46) | NOS3NOS2NOS1KDM4ETSHR | |
| SCHEMBL30684515 | 0.75 | NOS3 (0.46) | NOS3NOS2NOS1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |