SCHEMBL23376552

SCHEMBL23376552

CC1(C)c2ccccc2-c2cc(N(c3ccc(-c4ccc5oc6ccccc6c5c4)cc3)c3ccc4c(c3)-c3ccccc3C4(C)C)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
PGR P06401 1/20 0.34
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
TNKS O95271 1/20 0.33
ALK Q9UM73 1/20 0.32
AHR P35869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9916677 0.98 PLA2G2A (0.38) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL9916936 0.98 PLA2G2A (0.38) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL9916470 0.98 PLA2G2A (0.38) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL18802530 0.98 KDM4E (0.36) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL23376470 0.97 HSP90AA1 (0.35) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL25813474 0.96 MAPT (0.38) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL25814182 0.96 MAPT (0.38) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL9916930 0.96 PLA2G2A (0.37) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL17126429 0.96 HSP90AA1 (0.35) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL17126668 0.95 PLA2G2A (0.36) KDM4EMEN1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210147375-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147375-A1 MATERIALS FOR ELECTRONIC DEVICES PNMT, EFNA1, TES KDM4E 1633/4885MEN1 949/4885ALDH1A1 1820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.