Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27736912 | 0.80 | LPL (0.42) | RENLPLLIPGCYP4F2CYP4A11 | |
| SCHEMBL21292119 | 0.79 | LPL (0.49) | LPLLIPGPPARGPPARA | |
| SCHEMBL11204314 | 0.78 | MAOB (0.55) | RENTAAR1 | |
| SCHEMBL23380017 | 0.78 | TAAR1 (0.53) | TAAR1 | |
| SCHEMBL14402554 | 0.77 | LPL (0.56) | LPLLIPGPPARGPPARA | |
| SCHEMBL6685035 | 0.76 | L3MBTL1 (0.48) | CHRM2CHRM1SLC6A4SLC6A3 | |
| SCHEMBL12933285 | 0.75 | CHRM2 (0.59) | TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL23759882 | 0.75 | SIGMAR1 (0.50) | — | |
| SCHEMBL11949748 | 0.74 | CNR1 (0.42) | LPLLIPGTAAR1DRD2 | |
| SCHEMBL11910302 | 0.73 | FOLH1 (0.53) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021097057-A1 | 5-MEMBERED HETEROARYLAMINOSULFONAMIDES FOR TREATING CONDITIONS MEDIATED BY DEFICIENT CFTR ACTIVITY | GENZYME CORPORATION (US) | 2021-05-20 | — | — | WO | disclosed |