Diloxanide Furoate

Diloxanide Furoate

SCHEMBL23381

CN(C(=O)C(Cl)Cl)c1ccc(OC(=O)c2ccco2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 16/20 1.00
ALDH1A1 P00352 6/20 1.00
CYP3A4 P08684 1/20 1.00
HIF1A Q16665 1/20 1.00
PKM P14618 1/20 0.49
MAPT P10636 4/20 0.48
HSD17B10 Q99714 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 1/20 0.45
TP53 P04637 1/20 0.45
RECQL P46063 1/20 0.45
RAB9A P51151 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TSHR P16473 3/20 0.45
ESR1 P03372 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
CHRM1 P11229 1/20 0.44
ADORA1 P30542 1/20 0.44
ADRA1A P35348 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diloxanide Furoate SCHEMBL4706808 0.99 KMT2A (0.97) KMT2AALDH1A1CYP3A4HIF1APKM
SCHEMBL13381577 0.78 KMT2A (0.75) KMT2AALDH1A1CYP3A4HIF1APKM
Clefamide SCHEMBL28086196 0.78 ALDH1A1 (0.60) KMT2AALDH1A1CYP3A4HIF1APKM
Diloxanide Furoate SCHEMBL5267780 0.77 KMT2A (0.58) KMT2AALDH1A1CYP3A4HIF1APKM
SCHEMBL14130698 0.74 KMT2A (0.72) KMT2AALDH1A1CYP3A4HIF1APKM
SCHEMBL12591803 0.73 KMT2A (0.63) KMT2AALDH1A1CYP3A4HIF1APKM
SCHEMBL5943067 0.71 KMT2A (0.76) KMT2AALDH1A1PKMMAPTHSD17B10
SCHEMBL25054068 0.71 KMT2A (0.74) KMT2AALDH1A1CYP3A4HIF1APKM
SCHEMBL13802894 0.70 KMT2A (0.64) KMT2AALDH1A1CYP3A4HIF1APKM
SCHEMBL9047691 0.70 KMT2A (0.64) KMT2AALDH1A1CYP3A4HIF1APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3112 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741384-A1 FURONITRILE COMPOUND PRODUCTION METHOD AND CARBONATE ESTER PRODUCTION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-05-13 EP claimed
CN-119601660-A Carbon material and preparation method and application thereof 中国科学院大连化学物理研究所 2025-03-11 CN claimed
WO-2025009575-A1 FURONITRILE COMPOUND PRODUCTION METHOD AND CARBONATE ESTER PRODUCTION METHOD 三菱瓦斯化学株式会社 2025-01-09 WO claimed
CN-118368985-A Fungicidal compositions 先正达农作物保护股份公司 2024-07-19 CN claimed
CN-118354672-A Fungicidal compositions 先正达农作物保护股份公司 2024-07-16 CN claimed
US-20240122859-A1 EXTENDED RELEASE MULTIPLE UNIT PELLET SYSTEM COMPOSITION AND ITS PROCESS FOR THE PREPARATION NOKHA TRADING LLP (IN) 2024-04-18 US claimed
CN-117203324-A Novel yeast strains and their use in controlling plant pathogens 爱农创投有限公司 2023-12-08 CN claimed
US-20230381173-A1 METHODS AND PHARMACEUTICAL COMPOSITION FOR TREATING DISEASES TONGLI BIOMEDICAL CO., LTD. (CN) 2023-11-30 US claimed
WO-2023212494-A2 PREDICTIVE PESTICIDE RESISTANCE INFORMATION GENERATION AND USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-11-02 WO claimed
EP-4255175-A1 PREDICTIVE PESTICIDE RESISTANCE MAP GENERATION AND USE Pioneer Hi-Bred International, Inc. (US) 2023-10-11 EP claimed
WO-2000076505-A1 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO claimed
EP-0795596-B1 Fuel compositions SHELL INT RESEARCH (NL) 2000-10-11 EP claimed
CN-1216712-A Traditional Chinese medicine for treating cancer LU GAO (CN) 1999-05-19 CN claimed
CN-1199748-A Sugar boron polymer with protection function and its preparation, product and use ZHOU SHENGGANG (CN) 1998-11-25 CN claimed
CN-1161782-A Biological farm-chemical LI JINGWANG (CN) 1997-10-15 CN claimed
EP-0795596-A1 Fuel compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1997-09-17 EP claimed
CN-1137748-A Gas used as local and subcutaneous transmission carrier and microspheres filled with gas precursor IMARX PHARMACEUTICAL CORP (US) 1996-12-11 CN claimed
EP-0305968-A2 Compositions against protozoal diseases YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) 1989-03-08 EP claimed
US-4791112-A ANALGESICS, NAQRCOTIC ANTAGONISTS THE BOC GROUP, INC. (US) 1988-12-13 US claimed
US-3940537-A Fibrous mats ICI UNITED STATES INC. (US) 1976-02-24 US claimed