Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clefamide SCHEMBL672628 | 0.82 | LMNA (0.46) | ALDH1A1KMT2ALMNAMAPTNPSR1 | |
| Diloxanide Furoate SCHEMBL23381 | 0.78 | KMT2A (1.00) | ALDH1A1KMT2ACYP3A4HIF1ALMNA | |
| SCHEMBL11782643 | 0.77 | LMNA (0.49) | ALDH1A1KMT2ALMNAMAPTNPSR1 | |
| Diloxanide Furoate SCHEMBL4706808 | 0.77 | KMT2A (0.97) | ALDH1A1KMT2ACYP3A4HIF1ALMNA | |
| SCHEMBL11778961 | 0.75 | LMNA (0.51) | ALDH1A1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL11780196 | 0.74 | MC4R (0.53) | ALDH1A1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL11780000 | 0.74 | MC4R (0.53) | ALDH1A1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL11779835 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KMT2ALMNASMN1; SMN2NR3C1 | |
| Etofamide SCHEMBL1163863 | 0.72 | KCNH2 (0.46) | ALDH1A1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL11780552 | 0.70 | LMNA (0.45) | ALDH1A1KMT2ALMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |