Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.57 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.57 |
| ▸ | ECE1 | P42892 | 2/20 | 0.56 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238592 | 0.91 | ECE1 (0.64) | ALOX15MEN1KMT2AHCRTR1ERAP2 | |
| SCHEMBL1407979 | 0.89 | ALOX15 (0.68) | ALOX15MEN1KMT2AERAP2P2RY14 | |
| SCHEMBL30051539 | 0.89 | ALOX15 (0.68) | ALOX15MEN1KMT2AERAP2P2RY14 | |
| SCHEMBL23380932 | 0.89 | ALOX15 (0.61) | ALOX15MEN1KMT2AHCRTR1ERAP2 | |
| SCHEMBL1407978 | 0.89 | ALOX15 (0.68) | ALOX15MEN1KMT2AERAP2P2RY14 | |
| SCHEMBL14300977 | 0.89 | ALOX15 (0.61) | ALOX15MEN1KMT2AHCRTR1ERAP2 | |
| SCHEMBL23960347 | 0.88 | MMP9 (0.68) | MMP9MMP8MMP14 | |
| Water SCHEMBL28029902 | 0.88 | ERAP2 (0.67) | ALOX15MEN1KMT2AERAP2P2RY14 | |
| Water SCHEMBL28029903 | 0.88 | ERAP2 (0.67) | ALOX15MEN1KMT2AERAP2P2RY14 | |
| SCHEMBL13176572 | 0.87 | TACR1 (0.67) | ALOX15MEN1KMT2AACEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | ALOX15 3936/4885MEN1 938/4885KMT2A 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.