Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 17/20 | 0.68 |
| ▸ | MMP8 | P22894 | 13/20 | 0.68 |
| ▸ | MMP1 | P03956 | 7/20 | 0.68 |
| ▸ | MMP3 | P08254 | 6/20 | 0.68 |
| ▸ | MMP2 | P08253 | 18/20 | 0.65 |
| ▸ | MMP14 | P50281 | 3/20 | 0.63 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.63 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.63 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.63 |
| ▸ | MMP7 | P09237 | 1/20 | 0.63 |
| ▸ | MMP12 | P39900 | 1/20 | 0.63 |
| ▸ | MMP13 | P45452 | 1/20 | 0.63 |
| ▸ | MMP15 | P51511 | 1/20 | 0.63 |
| ▸ | MMP16 | P51512 | 1/20 | 0.63 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.63 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.63 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.63 |
| ▸ | MMP17 | Q9ULZ9 | 1/20 | 0.63 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25139560 | 0.89 | MMP9 (0.70) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL23381024 | 0.88 | ALOX15 (0.60) | MMP9MMP8MMP14 | |
| SCHEMBL12569733 | 0.87 | MMP9 (0.64) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL30051742 | 0.87 | ACE (0.68) | — | |
| SCHEMBL16298104 | 0.87 | MMP2 (0.64) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL25139559 | 0.86 | MMP9 (0.76) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL1407978 | 0.86 | ALOX15 (0.68) | — | |
| SCHEMBL1407979 | 0.86 | ALOX15 (0.68) | — | |
| SCHEMBL3787557 | 0.86 | MMP9 (0.72) | MMP9MMP8MMP1MMP3MMP2 | |
| SCHEMBL24814079 | 0.86 | MMP9 (0.69) | MMP9MMP8MMP1MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217019-A1 | RAS INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-28 | — | — | WO | disclosed |