Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475555 | 0.72 | MMP2 (0.46) | MMP2NEU3KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL23384070 | 0.68 | KMT2A (0.32) | — | |
| SCHEMBL4443502 | 0.66 | NEU3 (0.39) | MMP2NEU3KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL22819179 | 0.65 | KDM4A (0.33) | KDM4EL3MBTL1 | |
| SCHEMBL23384342 | 0.65 | GRIN2B (0.38) | PTGS2 | |
| SCHEMBL23363684 | 0.65 | GLO1 (0.42) | MMP2KDM4EHSD17B10GLO1NR3C1 | |
| SCHEMBL29757481 | 0.65 | GLO1 (0.42) | MMP2KDM4EHSD17B10GLO1NR3C1 | |
| SCHEMBL22108053 | 0.62 | RAB9A (0.40) | KDM4EL3MBTL1 | |
| SCHEMBL1474163 | 0.62 | GLO1 (0.42) | PIK3CAGLO1NR3C1L3MBTL1PTGS1 | |
| SCHEMBL29757502 | 0.61 | CA9 (0.31) | NEU3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021097039-A1 | TRIAZOLE CARBAMATE PYRIDYL SULFONAMIDES AS LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2021-05-20 | — | — | WO | disclosed |