Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338474 | 1.00 | NFE2L2 (0.36) | NFE2L2ALDH1A1EGFRERBB2TAS2R14 | |
| SCHEMBL2259985 | 0.94 | TSHR (0.37) | ALDH1A1MAPK1IDO1SMN1; SMN2TP53 | |
| SCHEMBL2259981 | 0.94 | TSHR (0.37) | ALDH1A1MAPK1IDO1SMN1; SMN2TP53 | |
| SCHEMBL2258867 | 0.89 | LTA4H (0.41) | ALDH1A1IDO1SMN1; SMN2POLBTP53 | |
| SCHEMBL12362842 | 0.89 | ACHE (0.43) | ALDH1A1EGFRIDO1SMN1; SMN2MAPT | |
| SCHEMBL21189910 | 0.89 | LTA4H (0.41) | ALDH1A1IDO1SMN1; SMN2POLBTP53 | |
| SCHEMBL2258863 | 0.89 | LTA4H (0.41) | ALDH1A1IDO1SMN1; SMN2POLBTP53 | |
| SCHEMBL21190015 | 0.89 | LTA4H (0.41) | ALDH1A1IDO1SMN1; SMN2POLBTP53 | |
| SCHEMBL23796902 | 0.87 | MEN1 (0.37) | ALDH1A1IDO1SMN1; SMN2MAPTTP53 | |
| SCHEMBL23796904 | 0.87 | MEN1 (0.37) | ALDH1A1IDO1SMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524781-B2 | Organosulfur compounds, a method of making organosulfur compounds and their use for inhibiting the growth of tumour cells | UNIVERSITY OF CAPE TOWN (ZA) | 2013-09-03 | — | — | US | disclosed |
| US-20110190368-A1 | Organosulfur Compounds, a Method of Making Organosulfur Compounds and their Use for Inhibiting the Growth of Tumour Cells | UNIVERSITY OF CAPE TOWN (ZA) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190368-A1 | Organosulfur Compounds, a Method of Making Organosulfur Compounds and their Use for Inhibiting the Growth of Tumour Cells | OR10J3, RCOR3, CBR3 | NFE2L2 1672/4885ALDH1A1 2183/4885EGFR 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.