Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS7 | Q9UKP4 | 13/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23354934 | 0.80 | ADAMTS7 (0.62) | ADAMTS7HDAC1 | |
| SCHEMBL29873733 | 0.80 | ADAMTS7 (0.62) | ADAMTS7HDAC1 | |
| SCHEMBL29873604 | 0.80 | ADAMTS7 (0.62) | ADAMTS7HDAC1 | |
| SCHEMBL24938697 | 0.79 | ADAMTS7 (0.57) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL23367505 | 0.78 | ADAMTS7 (0.60) | ADAMTS7HDAC1 | |
| SCHEMBL23354758 | 0.76 | ADAMTS7 (1.00) | ADAMTS7HDAC1 | |
| SCHEMBL23354809 | 0.75 | ADAMTS7 (0.93) | ADAMTS7HDAC1 | |
| SCHEMBL24938721 | 0.75 | ADAMTS7 (0.93) | ADAMTS7HDAC1 | |
| SCHEMBL23354855 | 0.75 | ADAMTS7 (0.93) | ADAMTS7HDAC1 | |
| SCHEMBL29873473 | 0.75 | ADAMTS7 (0.93) | ADAMTS7HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021094434-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-20 | — | — | WO | disclosed |