Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS7 | Q9UKP4 | 12/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23354910 | 0.79 | ADAMTS7 (0.65) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL29874194 | 0.79 | ADAMTS7 (0.65) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL23384697 | 0.79 | ADAMTS7 (0.61) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL23384608 | 0.75 | ADAMTS7 (0.62) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL29873787 | 0.74 | ADAMTS7 (0.66) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL23354853 | 0.74 | ADAMTS7 (0.66) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL23367298 | 0.74 | ADAMTS7 (0.55) | ADAMTS7HDAC1NPC1RAB9ANTRK1 | |
| SCHEMBL23354959 | 0.73 | ADAMTS7 (0.65) | ADAMTS7HDAC1NPC1RAB9A | |
| SCHEMBL23354855 | 0.73 | ADAMTS7 (0.93) | ADAMTS7HDAC1 | |
| SCHEMBL24938721 | 0.73 | ADAMTS7 (0.93) | ADAMTS7HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027985-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | ADAMTS7, MMP7, ADAMTS1 | ADAMTS7 1/4885HDAC1 615/4885NPC1 3408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.