Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30768024 | 0.81 | NOTUM (0.36) | PARP10PARP1NOTUMNISCHCDK2 | |
| SCHEMBL1405509 | 0.81 | NOTUM (0.36) | PARP10PARP1NOTUMNISCHCDK2 | |
| SCHEMBL1761215 | 0.79 | UGT2B17 (0.36) | UHRF1PARP10PARP11PARP1NOTUM | |
| SCHEMBL20939380 | 0.78 | NOTUM (0.42) | UHRF1PARP10PARP11PARP1NOTUM | |
| SCHEMBL29521546 | 0.77 | PARP10 (0.38) | UHRF1PARP10PARP11PARP1NOTUM | |
| SCHEMBL19411016 | 0.77 | PARP10 (0.38) | UHRF1PARP10PARP11PARP1NOTUM | |
| SCHEMBL1405476 | 0.76 | NOTUM (0.50) | PARP10PARP1NOTUMNISCHCDK2 | |
| SCHEMBL26431777 | 0.76 | ALDH1A1 (0.34) | PARP10PARP11PARP1NOTUMCDK2 | |
| SCHEMBL26656341 | 0.76 | HTR1D (0.38) | UHRF1PARP10PARP11PARP1NOTUM | |
| SCHEMBL24713940 | 0.76 | NOTUM (0.33) | PARP10PARP1NOTUMCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021093795-A1 | ROCK INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉朗来科技发展有限公司 | 2021-05-20 | — | — | WO | disclosed |