Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 12/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25897923 | 0.83 | DGAT1 (0.79) | DGAT1FOLH1 | |
| SCHEMBL22957840 | 0.83 | DGAT1 (0.79) | DGAT1FOLH1 | |
| SCHEMBL23386738 | 0.82 | DGAT1 (0.68) | DGAT1FOLH1 | |
| SCHEMBL563615 | 0.80 | DGAT1 (1.00) | DGAT1FOLH1 | |
| SCHEMBL563614 | 0.80 | DGAT1 (1.00) | DGAT1FOLH1 | |
| SCHEMBL22712914 | 0.78 | FOLH1 (1.00) | DGAT1FOLH1 | |
| SCHEMBL18161528 | 0.78 | FOLH1 (1.00) | DGAT1FOLH1 | |
| SCHEMBL14722195 | 0.78 | FOLH1 (1.00) | DGAT1FOLH1 | |
| SCHEMBL14722192 | 0.78 | FOLH1 (1.00) | DGAT1FOLH1 | |
| SCHEMBL20979154 | 0.77 | FOLH1 (0.75) | DGAT1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210145974-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | YALE UNIVERSITY | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210145974-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | ASGR1, LDLR, FCGR3B | DGAT1 3033/4885FOLH1 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.