Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.49 |
| ▸ | CDK2 | P24941 | 4/20 | 0.49 |
| ▸ | CDK1 | P06493 | 3/20 | 0.49 |
| ▸ | GSK3A | P49840 | 5/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334015 | 0.99 | GSK3B (0.50) | GSK3BCDK2CDK1GSK3ACHRM3 | |
| SCHEMBL1377235 | 0.85 | GSK3B (0.52) | GSK3BCDK2CDK1GSK3ASMN1; SMN2 | |
| SCHEMBL2333341 | 0.83 | GSK3B (0.53) | GSK3BCDK2CDK1GSK3AMAPK1 | |
| SCHEMBL4381668 | 0.80 | GSK3B (0.60) | GSK3BCDK2CDK1GSK3AMAPK1 | |
| SCHEMBL2332408 | 0.79 | GSK3B (0.60) | GSK3BCDK2CDK1GSK3AMAPK1 | |
| SCHEMBL4392816 | 0.76 | GSK3B (0.61) | GSK3BCDK2CDK1GSK3AMAPK1 | |
| SCHEMBL1461697 | 0.75 | GSK3B (0.82) | GSK3BCDK2CDK1GSK3AMAPK1 | |
| SCHEMBL2337608 | 0.72 | GSK3B (0.49) | GSK3BCDK2CDK1GSK3A | |
| SCHEMBL4327883 | 0.69 | ALDH1A1 (0.59) | CHRM3ALDH1A1SMN1; SMN2 | |
| SCHEMBL2361748 | 0.69 | GSK3B (0.63) | GSK3BCDK2CDK1GSK3AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572200-B1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2011-08-17 | — | — | EP | claimed |