Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | LPL | P06858 | 7/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57994 | 0.80 | LPL (0.46) | CA1CA2CA9LPLLIPG | |
| SCHEMBL1129409 | 0.75 | LIPG (0.43) | CA1CA2CA9LPLLIPG | |
| SCHEMBL23407749 | 0.75 | CYP3A4 (0.33) | CYP3A4TSHRNR4A1ALDH1A1MAPK1 | |
| SCHEMBL3239432 | 0.74 | LPL (0.38) | CA1CA2CA9LPLLIPG | |
| SCHEMBL12632055 | 0.73 | LPL (0.40) | CA1CA2CA9LPLLIPG | |
| SCHEMBL23391539 | 0.72 | CYP3A4 (0.41) | CA1CA2CA9CYP3A4TSHR | |
| SCHEMBL273483 | 0.71 | NR4A1 (0.61) | CA1CA2CA9CYP3A4TSHR | |
| SCHEMBL23391578 | 0.70 | TTR (0.40) | TSHRMAPK1AAK1 | |
| SCHEMBL14962342 | 0.70 | LPL (0.40) | CA1CA2CA9LPLLIPG | |
| SCHEMBL16194387 | 0.70 | AAK1 (0.36) | CA1CA2CA9LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4063373-A1 | NOVEL METALLO-BETA-LACTAMASE INHIBITOR CREATED IN MULTI-DRUG RESISTANT BACTERIA, AND PREPARATION METHOD THEREFOR | Myongji University Industry and Academia Cooperation Foundation (KR) | 2022-09-28 | — | — | EP | disclosed |
| US-11395829-B2 | Inhibitors of metallo-beta-lactamases produced by multidrug-resistant bacteria | MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) | 2022-07-26 | — | — | US | disclosed |
| US-20210154216-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES PRODUCED BY MULTIDRUG-RESISTANT BACTERIA | MYONGJI UNIVERSITY INDUSTRY AND ACADEMIA COOPERATION FOUNDATION (KR) | 2021-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210154216-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES PRODUCED BY MULTIDRUG-RESISTANT BACTERIA | MANBA, MGAM, GUSB | CA1 2178/4885CA2 1491/4885CA9 1266/4885 |
| US-11395829-B2 | Inhibitors of metallo-beta-lactamases produced by multidrug-resistant bacteria | MANBA, MGAM, GUSB | CA1 2178/4885CA2 1491/4885CA9 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.