SCHEMBL233939

SCHEMBL233939

COc1[c]ccc(/C=C/[N+](=O)[O-])c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
VCP P55072 6/20 0.56
FBP1 P09467 10/20 0.55
EGFR P00533 2/20 0.52
SYK P43405 2/20 0.52
GALR2 O43603 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.52
MAPK1 P28482 1/20 0.52
HTT P42858 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
ABL1 P00519 1/20 0.45
ABL2 P42684 1/20 0.45
TLR4 O00206 3/20 0.44
TLR2 O60603 3/20 0.44
PRMT1 Q99873 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233940 1.00 VCP (0.56) VCPFBP1EGFRSYKGALR2
SCHEMBL29279535 0.80 FBP1 (0.54) VCPFBP1EGFRSYKGALR2
SCHEMBL29279591 0.80 FBP1 (0.54) VCPFBP1EGFRSYKGALR2
SCHEMBL2791518 0.76 TYR (0.44) ALDH1A1LMNAMAPTMAPK1HTT
SCHEMBL1172170 0.76 TYR (0.44) ALDH1A1LMNAMAPTMAPK1HTT
SCHEMBL1172169 0.76 TYR (0.44) ALDH1A1LMNAMAPTMAPK1HTT
SCHEMBL360286 0.74 ALDH1A1 (0.47) ALDH1A1LMNAMAPTHTTSMN1; SMN2
SCHEMBL15475023 0.73 TUBB1 (0.51) ALDH1A1MAPTSMN1; SMN2
SCHEMBL15475022 0.73 TUBB1 (0.51) ALDH1A1MAPTSMN1; SMN2
SCHEMBL793160 0.72 VCP (1.00) VCPFBP1EGFRSYKGALR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2718458-B1 NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE BIOSYNTH AG (CH) 2015-07-08 EP claimed
US-20140212905-A1 Novel Method for Detection of Beta-D-Glucuronidase BIOSYNTH AG (CH) 2014-07-31 US claimed
EP-2718458-A1 NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE Biosynth AG (CH) 2014-04-16 EP claimed
WO-2012168415-A1 NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE BIOSYNTH AG (CH) 2012-12-13 WO claimed
EP-2532753-A1 Method for detection of beta-D-glucuronidase Biosynth AG (CH) 2012-12-12 EP claimed
EP-4376887-A2 MATERIALS AND METHODS OF MAKING OR USING IL-23R BINDING PROTEINS Janssen Biotech, Inc. (US) 2024-06-05 EP disclosed
WO-2024112907-A1 SYSTEMS, METHODS, AND KITS FOR DETECTING PROTEIN INTERACTIONS ADVANCED CELL DIAGNOSTICS, INC. (US) 2024-05-30 WO disclosed
US-20240035073-A1 METHODS FOR DETECTING PROTEINS AND FOR CO-DETECTING PROTEINS AND NUCLEIC ACIDS, AND KITS FOR THE SAME ADVANCED CELL DIAGNOSTICS, INC. 2024-02-01 US disclosed
EP-4225379-A1 METHODS FOR TREATING CANCERS WITH ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS Agensys, Inc. (US) 2023-08-16 EP disclosed
EP-4168039-A1 MARKERS FOR USE IN METHODS FOR TREATING CANCERS WITH ANTIBODY DRUG CONJUGATES (ADC) Agensys, Inc. (US) 2023-04-26 EP disclosed
WO-2023009891-A2 MATERIALS AND METHODS OF MAKING OR USING IL-23R BINDING PROTEINS JANSSEN BIOTECH, INC. (US) 2023-02-02 WO disclosed
WO-2021257938-A1 MARKERS FOR USE IN METHODS FOR TREATING CANCERS WITH ANTIBODY DRUG CONJUGATES (ADC) AGENSYS, INC, (US) 2021-12-23 WO disclosed
EP-2718458-B1 NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE BIOSYNTH AG (CH) 2015-07-08 EP disclosed
US-20140212905-A1 Novel Method for Detection of Beta-D-Glucuronidase BIOSYNTH AG (CH) 2014-07-31 US disclosed
EP-2718458-A1 NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE Biosynth AG (CH) 2014-04-16 EP disclosed
WO-2012168415-A1 NOVEL METHOD FOR DETECTION OF BETA-D-GLUCURONIDASE BIOSYNTH AG (CH) 2012-12-13 WO disclosed
EP-2532753-A1 Method for detection of beta-D-glucuronidase Biosynth AG (CH) 2012-12-12 EP disclosed
WO-2012006187-A2 METHODS AND DEVICES FOR THE SELECTIVE DETECTION OF MICROORGANISMS C3 JIAN, INC. (US) 2012-01-12 WO disclosed
US-20120003661-A1 METHODS AND DEVICES FOR THE SELECTIVE DETECTION OF MICROORGANISMS C3 JIAN, INC. (US) 2012-01-05 US disclosed
EP-0097506-A2 Method for diagnosis of mastitis using enzyme N-acetyl-beta-D-glucosaminidase and reaction systems for use in method The State of Queensland (AU) 1984-01-04 EP disclosed