Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 9/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886476 | 0.76 | ALDH1A1 (0.55) | GLSDPP4CA12CA1CA2 | |
| SCHEMBL8013071 | 0.74 | DPP4 (0.49) | EPHX1DPP4CA12CA1CA2 | |
| SCHEMBL14780646 | 0.74 | GLS (0.40) | EPHX1GLSDPP4METAP2DPP7 | |
| SCHEMBL13275296 | 0.74 | GLS (0.40) | EPHX1GLSDPP4METAP2DPP7 | |
| SCHEMBL20629881 | 0.73 | EPHX1 (0.36) | EPHX1CA12CA1CA2MMP2 | |
| SCHEMBL21335219 | 0.73 | CPB2 (0.36) | GLSDPP4METAP2DPP7 | |
| SCHEMBL764548 | 0.73 | GLS (0.47) | EPHX1GLSDPP4DPP7 | |
| SCHEMBL22968844 | 0.72 | DPP4 (0.46) | EPHX1DPP4DPP7 | |
| SCHEMBL20877709 | 0.72 | DPP4 (0.46) | EPHX1DPP4DPP7 | |
| SCHEMBL18401046 | 0.72 | DPP4 (0.46) | EPHX1DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825312-A1 | INTERMEDIATES FOR PREPARING INHIBITORS OF HEPATITIS C VIRUS | Gilead Pharmasset LLC (US) | 2021-05-26 | — | — | EP | disclosed |