Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LOX | P28300 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203591 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1GAALOXL2MEN1 | |
| SCHEMBL25181401 | 0.75 | F10 (0.38) | KDM4EALDH1A1GAABRD4MEN1 | |
| SCHEMBL25189286 | 0.75 | PTPN11 (0.54) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL17789604 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL30412517 | 0.74 | BRD4 (0.40) | BRD4KMT2AMAPT | |
| SCHEMBL26230874 | 0.73 | GAA (0.42) | KDM4EALDH1A1GAAHDAC4BRD4 | |
| SCHEMBL9069963 | 0.72 | KDM4E (0.49) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL25182494 | 0.72 | TAS1R3 (0.45) | — | |
| SCHEMBL16369810 | 0.72 | POLB (0.48) | ALDH1A1HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL17987756 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825304-A1 | ANTIBODY-DRUG CONJUGATES AND THE USE OF SAME IN THERAPY | Mc SAF (FR) | 2021-05-26 | — | — | EP | disclosed |
| US-9533974-B2 | Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates | MICHIGAN DIAGNOSTICS, LLC (US) | 2017-01-03 | — | — | US | disclosed |