Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.34 |
| ▸ | CA6 | P23280 | 3/20 | 0.32 |
| ▸ | TPMT | P51580 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SELL | P14151 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23395872 | 0.90 | CA5A (0.47) | CA5ALMNAHPGD | |
| SCHEMBL23395956 | 0.87 | PARP1 (0.33) | CA5A | |
| SCHEMBL23396193 | 0.86 | CA12 (0.47) | CA12CA1CA2CA9CA7 | |
| SCHEMBL23395836 | 0.79 | — | — | |
| SCHEMBL23395885 | 0.78 | PLA2G2A (0.33) | MAPTTDP1 | |
| SCHEMBL23395859 | 0.77 | TTR (0.31) | — | |
| SCHEMBL23396150 | 0.75 | CA5A (0.52) | CA12CA1CA2CA9CA7 | |
| SCHEMBL23396393 | 0.75 | ALDH5A1 (0.40) | CA5AKDM4EALDH1A1TP53MAPT | |
| SCHEMBL23395818 | 0.73 | CA5A (0.31) | CA5A | |
| SCHEMBL23395915 | 0.71 | CA12 (0.62) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230281-B1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | BAYER AG (DE) | 2021-05-26 | — | — | EP | disclosed |