Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 14/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 14/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12594040 | 0.89 | GRM5 (0.41) | GRM5P2RX3P2RX2LMNASMN1; SMN2 | |
| SCHEMBL1107566 | 0.79 | ALDH1A1 (0.45) | GRM5P2RX3P2RX2ACACB | |
| SCHEMBL31130428 | 0.77 | KMT2A (0.48) | SMN1; SMN2 | |
| SCHEMBL14495743 | 0.74 | CA5A (0.52) | LMNASMN1; SMN2 | |
| SCHEMBL1107609 | 0.74 | ALDH1A1 (0.42) | GRM5P2RX3P2RX2LMNA | |
| SCHEMBL12742709 | 0.72 | GCK (0.55) | — | |
| SCHEMBL30055794 | 0.69 | CNR2 (0.44) | GRM5P2RX3P2RX2LMNA | |
| SCHEMBL17321002 | 0.68 | KAT6A (0.48) | LMNASMN1; SMN2 | |
| SCHEMBL2668774 | 0.68 | GCK (0.47) | P2RX3P2RX2ACACB | |
| SCHEMBL23396295 | 0.67 | IKBKB (0.41) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230281-B1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | BAYER AG (DE) | 2021-05-26 | — | — | EP | disclosed |