Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23396265 | 0.81 | POLB (0.32) | MEN1KMT2APOLB | |
| SCHEMBL23396016 | 0.76 | CHEK2 (0.37) | IKBKBCHEK2MEN1KMT2ACYP4F2 | |
| SCHEMBL23395912 | 0.74 | EPHX2 (0.41) | IKBKBCHEK2MEN1KMT2ACYP4F2 | |
| SCHEMBL9013908 | 0.70 | CHEK2 (0.48) | IKBKBCHEK2MEN1KMT2ACYP4F2 | |
| SCHEMBL2091338 | 0.70 | EPHX2 (0.57) | IKBKBCYP4F2CYP4A11CHUKNAMPT | |
| SCHEMBL16220677 | 0.69 | EPHX2 (0.56) | CHEK2CYP4F2CYP4A11HRH3NAMPT | |
| SCHEMBL9013886 | 0.69 | CASP6 (0.53) | IKBKBCHEK2KMT2ACYP4F2CYP4A11 | |
| SCHEMBL2094409 | 0.69 | HRH3 (0.49) | IKBKBCHEK2CYP4F2CYP4A11HRH3 | |
| SCHEMBL227303 | 0.69 | CYP4F2 (0.49) | IKBKBCHEK2KMT2ACYP4F2CYP4A11 | |
| SCHEMBL693534 | 0.68 | CYP4F2 (0.48) | IKBKBCHEK2KMT2ACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230281-B1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | BAYER AG (DE) | 2021-05-26 | — | — | EP | disclosed |