Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3424767 | 0.98 | TAAR1 (0.40) | TAAR1ALDH1A1LMNAIDO1AOC3 | |
| SCHEMBL4841912 | 0.85 | TAAR1 (0.57) | TAAR1ALDH1A1IDO1AOC3MPO | |
| Hydrochloric Acid SCHEMBL4717599 | 0.84 | TAAR1 (0.55) | TAAR1ALDH1A1IDO1AOC3MPO | |
| SCHEMBL27918771 | 0.83 | MPO (0.50) | TAAR1ALDH1A1LMNAMPOMAPT | |
| SCHEMBL13988381 | 0.79 | TAAR1 (0.39) | TAAR1ALDH1A1IDO1AOC3MPO | |
| SCHEMBL3903028 | 0.77 | TAAR1 (0.68) | TAAR1IDO1AOC3MPOSLC6A4 | |
| SCHEMBL7341280 | 0.77 | PTGER4 (0.57) | ALDH1A1PTGER1PTGER4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL4323161 | 0.77 | TAAR1 (0.38) | TAAR1ALDH1A1IDO1AOC3MPO | |
| SCHEMBL27491064 | 0.73 | TAAR1 (0.41) | TAAR1ALDH1A1LMNAIDO1AOC3 | |
| SCHEMBL7202777 | 0.72 | TAAR1 (0.42) | TAAR1LMNAIDO1F2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663960-B1 | AMIDINES AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2011-08-24 | — | — | EP | disclosed |