Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.42 |
| ▸ | PNMT | P11086 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841912 | 0.78 | TAAR1 (0.57) | TAAR1IDO1F2HPGD | |
| Hydrochloric Acid SCHEMBL4717599 | 0.76 | TAAR1 (0.55) | TAAR1IDO1HPGD | |
| Hydrochloric Acid SCHEMBL4714930 | 0.76 | TAAR1 (0.56) | TAAR1PNMTSMN1; SMN2HTTLMNA | |
| SCHEMBL3680160 | 0.76 | LMNA (0.45) | TAAR1SMN1; SMN2HTTLMNAIDO1 | |
| SCHEMBL3630056 | 0.76 | MTNR1A (0.56) | HTTHPGD | |
| SCHEMBL8109289 | 0.75 | KEAP1 (0.54) | DPP4SMN1; SMN2KDM4E | |
| SCHEMBL29405036 | 0.74 | PNMT (0.63) | TAAR1PNMTDPP4SMN1; SMN2KDM4E | |
| SCHEMBL15247 | 0.74 | PNMT (0.63) | TAAR1PNMTDPP4SMN1; SMN2KDM4E | |
| SCHEMBL632593 | 0.73 | DPP4 (0.48) | TAAR1PNMTDPP4HTR2ASMN1; SMN2 | |
| SCHEMBL3051426 | 0.72 | TAAR1 (0.61) | TAAR1PNMTDPP4HTR2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030104348-A1 | Kidney perfusion solution containing nitric oxide donor | HERMACELL PERFUSION, INC. | 2003-06-05 | — | — | US | claimed |