Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023123 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HIF1ALMNARECQLVCAM1 | |
| SCHEMBL9913587 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HIF1ALMNARECQLVCAM1 | |
| SCHEMBL545367 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HIF1ALMNARECQLVCAM1 | |
| SCHEMBL10315544 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HIF1ALMNARECQLVCAM1 | |
| SCHEMBL29990481 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HIF1ALMNARECQLVCAM1 | |
| SCHEMBL31023151 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HIF1ALMNARECQLVCAM1 | |
| SCHEMBL14880650 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HIF1ALMNARECQLVCAM1 | |
| SCHEMBL3120356 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HIF1ALMNARECQLVCAM1 | |
| SCHEMBL2339087 | 0.76 | LMNA (0.55) | ALDH1A1HIF1ALMNARECQLVCAM1 | |
| SCHEMBL565080 | 0.76 | RIPK1 (0.45) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |