Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.40 |
| ▸ | USP2 | O75604 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235438 | 0.83 | LTA4H (0.56) | FDPSLTA4HHDAC1HDAC6CYP1A2 | |
| SCHEMBL29941724 | 0.80 | FDPS (0.54) | FDPSLTA4HHDAC1HDAC6CYP1A2 | |
| SCHEMBL5062453 | 0.80 | FDPS (0.54) | FDPSLTA4HHDAC1HDAC6CYP1A2 | |
| Hydrochloric Acid SCHEMBL21174543 | 0.79 | FDPS (0.53) | FDPSLTA4HHDAC1HDAC6CYP1A2 | |
| SCHEMBL8444477 | 0.78 | FDPS (0.46) | FDPSLTA4HHDAC1HDAC6CYP1A2 | |
| SCHEMBL6935229 | 0.78 | FDPS (0.49) | FDPSLTA4HHDAC1HDAC6CYP1A2 | |
| SCHEMBL31024294 | 0.77 | FDPS (0.51) | FDPSLTA4HHDAC1HDAC6CYP1A2 | |
| SCHEMBL10163117 | 0.77 | FDPS (0.51) | FDPSLTA4HHDAC1HDAC6CYP1A2 | |
| SCHEMBL28817988 | 0.77 | FDPS (0.54) | FDPSLTA4HHDAC1HDAC6CYP1A2 | |
| SCHEMBL6125409 | 0.77 | FDPS (0.54) | FDPSLTA4HHDAC1HDAC6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473625-B1 | PREPARATION METHOD FOR CHIRAL PYRROLOPYRIMIDINE COMPOUND | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2021-06-02 | — | — | EP | disclosed |