Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444477 | 0.85 | FDPS (0.46) | FDPSLTA4HPNPUSP2HSD17B10 | |
| SCHEMBL6259635 | 0.79 | FDPS (0.55) | FDPSLTA4HUSP2HSD17B10TSHR | |
| SCHEMBL30166038 | 0.79 | FDPS (0.55) | FDPSLTA4HUSP2HSD17B10TSHR | |
| SCHEMBL9936014 | 0.79 | FDPS (0.62) | FDPSLTA4HUSP2HSD17B10TSHR | |
| SCHEMBL3044440 | 0.78 | FDPS (0.63) | FDPSLTA4HPNPHDAC1HDAC6 | |
| SCHEMBL8839833 | 0.78 | FDPS (0.51) | FDPSLTA4HTSHRBLMHBB | |
| SCHEMBL23398227 | 0.78 | FDPS (0.50) | FDPSLTA4HUSP2HSD17B10TSHR | |
| Desciclovir SCHEMBL2028 | 0.77 | PNP (0.52) | PNPUSP2HSD17B10TSHREDNRA | |
| Desciclovir SCHEMBL29403096 | 0.77 | PNP (0.52) | PNPUSP2HSD17B10TSHREDNRA | |
| SCHEMBL4028187 | 0.76 | MEN1 (0.47) | PNPUSP2HSD17B10TSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915874-B1 | PROCESS OF PREPARATION OF VALACYCLOVIR AND RELEVANT INTERMEDIATES | IND CHIMICA SRL (IT) | 2003-12-10 | — | — | EP | disclosed |
| EP-0804547-A4 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | UNIV COLUMBIA (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0915874-A2 | PROCESS OF PREPARATION OF VALACYCLOVIR AND RELEVANT INTERMEDIATES | INDUSTRIALE CHIMICA S.r.l. (IT) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003553-A1 | PROCESS OF PREPARATION OF VALACYCLOVIR AND RELEVANT INTERMEDIATES | INDUSTRIALE CHIMICA S.R.L. (IT) | 1998-01-29 | — | — | WO | disclosed |
| EP-0804547-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 1997-11-05 | — | — | EP | disclosed |