Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23399504 | 0.85 | HTR7 (0.38) | MAPTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL23402711 | 0.81 | MAPT (0.44) | MAPTCDK8ACVR1NPC1RAB9A | |
| SCHEMBL20320421 | 0.80 | MAPT (0.67) | MAPTCDK8ACVR1CREBBPNPC1 | |
| SCHEMBL27217096 | 0.78 | MAPT (0.50) | MAPTCDK8ACVR1CREBBPNPC1 | |
| SCHEMBL23398433 | 0.78 | NPC1 (0.51) | MAPTNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL23400439 | 0.78 | ESR1 (0.42) | MAPTCDK8ACVR1NR1H3POLB | |
| SCHEMBL23402647 | 0.78 | TDP1 (0.46) | MAPTCDK8ACVR1NPC1RAB9A | |
| SCHEMBL23401679 | 0.77 | PKM (0.41) | MAPTCDK8ACVR1NPC1RAB9A | |
| SCHEMBL23402072 | 0.77 | LMNA (0.43) | MAPTRAB9ANR1H2NR1H3POLB | |
| SCHEMBL23400366 | 0.77 | GRIA2 (0.43) | MAPTCDK8ACVR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |