Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23399682 | 0.82 | MEN1 (0.41) | KMT2ABRD4MAPK13CSNK1DCSNK1E | |
| SCHEMBL12970429 | 0.81 | CYP2A6 (0.50) | ALDH1A1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL23398666 | 0.80 | JMJD6 (0.47) | KMT2AALDH1A1HPGDJMJD6NPC1 | |
| SCHEMBL14236334 | 0.80 | ALDH1A1 (0.53) | KMT2ABACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL5541734 | 0.79 | CSNK1D (0.57) | KMT2AJMJD6MAPK13CSNK1DCSNK1E | |
| SCHEMBL3761896 | 0.79 | COMT (0.49) | KMT2AALDH1A1HPGDHSD17B10ADORA3 | |
| SCHEMBL25731619 | 0.79 | RAB9A (0.51) | KMT2AALDH1A1HPGDHSD17B10ADORA3 | |
| SCHEMBL23398728 | 0.78 | PTGIR (0.44) | KMT2AALDH1A1PTGIRRAB9ANR1H3 | |
| SCHEMBL13772717 | 0.78 | BRAF (0.56) | KMT2ABCL2L1ADORA1JMJD6MAPK13 | |
| SCHEMBL8267917 | 0.78 | ADORA3 (0.50) | KMT2AALDH1A1HPGDHSD17B10ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |