SCHEMBL23399233

SCHEMBL23399233

CC(C)Cc1c[nH]n(CC(C)C)c1=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM5A P29375 1/20 0.33
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31
DAO P14920 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23400389 0.87 SMN1; SMN2 (0.35) SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1
SCHEMBL23400475 0.85 ALDH1A1 (0.33) ALDH1A1KDM5ADAOGABRA1GABRB2
SCHEMBL23398383 0.82 ALDH1A1 (0.49) ALDH1A1HTTKDM5A
SCHEMBL23402389 0.82 ALDH1A1 (0.35) SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1
SCHEMBL23401045 0.80 ALDH1A1 (0.40) SMN1; SMN2TDP1L3MBTL1ALDH1A1MEN1
SCHEMBL23402801 0.80 CTRC (0.35) SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1
SCHEMBL23398805 0.77 SMN1; SMN2 (0.36) SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1
SCHEMBL23400488 0.77 GABRA1 (0.36) TSHRALDH1A1KDM5ADAOGABRA1
SCHEMBL23399751 0.76 KDM5A (0.33) KDM5ADAOGABRA1GABRB2
SCHEMBL23401215 0.76 SMN1; SMN2 (0.35) SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed