SCHEMBL23399402

SCHEMBL23399402

CCn1nc(-c2cccc(C)c2)c(C(C)C)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LDHA P00338 1/20 0.37
LDHB P07195 1/20 0.37
SRC P12931 1/20 0.37
RIPK2 O43353 1/20 0.36
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
NFKB1 P19838 1/20 0.35
RAB9A P51151 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAPK14 Q16539 5/20 0.34
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
LMNA P02545 1/20 0.34
TLR8 Q9NR97 1/20 0.34
HTR2C P28335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399532 0.90 ESR1 (0.41) TRPM8LDHALDHBSRCRIPK2
SCHEMBL23402342 0.88 NR1H2 (0.36) NPC1TRPM8LDHALDHBSRC
SCHEMBL23401599 0.87 TLR8 (0.41) MAPTTLR8TP53
SCHEMBL23403662 0.84 MEN1 (0.46) L3MBTL1MAPTSMN1; SMN2
SCHEMBL23401575 0.83 RAB9A (0.38) NPC1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL23402561 0.83 NPC1 (0.41) NPC1TRPM8L3MBTL1RIPK2RAB9A
SCHEMBL23401281 0.82 RECQL (0.41) NPC1L3MBTL1LDHALDHBSRC
SCHEMBL23401299 0.82 SRC (0.50) NPC1LDHALDHBSRCRIPK2
SCHEMBL23403398 0.82 NPC1 (0.37) NPC1TRPM8L3MBTL1SRCRIPK2
SCHEMBL23400837 0.81 L3MBTL1 (0.39) NPC1TRPM8L3MBTL1RIPK2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed