SCHEMBL23401281

SCHEMBL23401281

Cc1cccc(-c2nn(C)c(O)c2C(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.41
SRC P12931 2/20 0.39
LDHA P00338 1/20 0.39
LDHB P07195 1/20 0.39
TDP2 O95551 1/20 0.39
RIPK2 O43353 1/20 0.38
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
MAPK14 Q16539 2/20 0.36
TGFBR1 P36897 1/20 0.36
IDO1 P14902 1/20 0.35
HCRTR1 O43613 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23401299 0.85 SRC (0.50) SRCLDHALDHBRIPK2RAB9A
SCHEMBL18770442 0.83 RECQL (0.58) RECQLALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL23399532 0.82 ESR1 (0.41) SRCLDHALDHBRIPK2MAPT
SCHEMBL23399402 0.82 NPC1 (0.38) SRCLDHALDHBRIPK2RAB9A
SCHEMBL23400286 0.82 ALDH1A1 (0.47) SRCLDHALDHBRIPK2RAB9A
SCHEMBL23399653 0.82 RIPK2 (0.52) SRCLDHALDHBRIPK2RAB9A
SCHEMBL23398748 0.81 TDP2 (0.42) SRCTDP2RIPK2RAB9ANPC1
SCHEMBL23400788 0.81 RECQL (0.42) RECQLLDHALDHBTDP2RAB9A
SCHEMBL23401908 0.81 L3MBTL1 (0.48) SRCLDHALDHBRAB9ANPC1
SCHEMBL23400532 0.81 NPC1 (0.48) RAB9ANPC1ALDH1A1MAPTNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed