SCHEMBL23400014

SCHEMBL23400014

CCCCc1c(O)nn(-c2ccc(C)cc2)c1C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK8 P49336 2/20 0.36
ALDH1A1 P00352 5/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
TP53 P04637 2/20 0.35
NFKB1 P19838 2/20 0.35
MAPK1 P28482 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GMNN O75496 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
ESR1 P03372 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399379 0.93 USP2 (0.41) CDK8ALDH1A1CNR1CNR2TP53
SCHEMBL23402119 0.89 USP2 (0.41) ALDH1A1CNR1CNR2MAPTKMT2A
SCHEMBL23398490 0.87 CDK8 (0.41) CDK8ALDH1A1CNR1CNR2TP53
SCHEMBL23399654 0.84 RIPK2 (0.41) ALDH1A1TP53MAPTLMNAMAPK14
SCHEMBL23400163 0.83 CDK8 (0.36) CDK8ALDH1A1CNR1CNR2TP53
SCHEMBL23399686 0.82 ALDH1A1 (0.41) ALDH1A1TP53NFKB1MAPK1MAPT
SCHEMBL23398747 0.81 KMT2A (0.37) ALDH1A1TP53NFKB1MAPK1MAPT
SCHEMBL23403425 0.81 CDK8 (0.36) CDK8ALDH1A1CNR1CNR2TP53
SCHEMBL23402658 0.80 USP2 (0.43) ALDH1A1CNR1CNR2TP53NFKB1
SCHEMBL23402663 0.80 TP53 (0.36) CDK8ALDH1A1TP53NFKB1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed