SCHEMBL23400950

SCHEMBL23400950

CCCn1nc(-c2ccccc2C)c(C(C)(C)C)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.42
PTGS2 P35354 1/20 0.35
TLR8 Q9NR97 1/20 0.34
MAPT P10636 2/20 0.34
TSHR P16473 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CRHBP P24387 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
CRHR2 Q13324 1/20 0.34
POLB P06746 1/20 0.32
TRPM8 Q7Z2W7 1/20 0.32
DPP4 P27487 1/20 0.32
SLC9A1 P19634 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
USP2 O75604 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402386 0.92 ESR1 (0.38) ESR1TLR8MAPTMEN1KMT2A
SCHEMBL23402204 0.89 TRPM8 (0.35) ESR1TLR8MAPTTSHRMEN1
SCHEMBL23403633 0.83 ESR1 (0.46) ESR1PTGS2TLR8MAPTTSHR
SCHEMBL23402129 0.83 ATM (0.34) MAPTTSHRDPP4GABRA1GABRB2
SCHEMBL23403601 0.82 MEN1 (0.48) ESR1MAPTTSHRMEN1KMT2A
SCHEMBL23400928 0.81 TDP2 (0.36) MAPTTSHRMEN1KMT2ADPP4
SCHEMBL23403352 0.81 ESR1 (0.44) ESR1PTGS2TLR8MAPTTSHR
SCHEMBL23399475 0.80 ESR1 (0.43) ESR1PTGS2TLR8MAPTTSHR
SCHEMBL23401012 0.78 ESR1 (0.42) ESR1PTGS2TLR8MAPTTSHR
SCHEMBL23403292 0.78 ESR1 (0.48) ESR1PTGS2MAPTTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed