SCHEMBL23402129

SCHEMBL23402129

Cc1ccccc1-c1nn(CC(C)C)c(O)c1C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPK13 O15264 1/20 0.31
MAPK12 P53778 1/20 0.31
MAPK11 Q15759 1/20 0.31
MAPK14 Q16539 1/20 0.31
DPP4 P27487 1/20 0.31
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402204 0.85 TRPM8 (0.35) ATMGABRA1GABRB2KDM4EALDH1A1
SCHEMBL23402212 0.83 GABRA1 (0.38) ATMGABRA1GABRB2KDM4EALDH1A1
SCHEMBL23400950 0.83 ESR1 (0.42) GABRA1GABRB2DPP4USP2MAPT
SCHEMBL23402137 0.82 CNR2 (0.37) ATMKDM4EALDH1A1L3MBTL1MAPK14
SCHEMBL23398750 0.81 LDHA (0.34) ATMGABRA1GABRB2KDM4EALDH1A1
SCHEMBL23398508 0.81 ESR1 (0.42) GABRA1GABRB2KDM4EALDH1A1MAPK13
SCHEMBL23402386 0.81 ESR1 (0.38) MAPT
SCHEMBL23402074 0.80 KDM5A (0.34) ATMGABRA1GABRB2KDM4EMAPK13
SCHEMBL23401610 0.80 GABRA1 (0.33) ATMGABRA1GABRB2KDM4EMAPK13
SCHEMBL23400152 0.79 ATM (0.34) ATMKDM4EALDH1A1L3MBTL1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed