SCHEMBL23401201

SCHEMBL23401201

Cc1cccc(-c2nn(CC(C)C)c(O)c2C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
SRC P12931 1/20 0.38
ICMT O60725 1/20 0.37
IDO1 P14902 2/20 0.36
RIPK2 O43353 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
MAPK14 Q16539 1/20 0.35
NPC1 O15118 1/20 0.35
NFKB1 P19838 1/20 0.35
RAB9A P51151 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NR1H2 P55055 3/20 0.35
POLB P06746 1/20 0.35
SLC16A3 O15427 1/20 0.35
SLC16A1 P53985 1/20 0.35
LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402342 0.86 NR1H2 (0.36) GABRA1GABRB2SRCICMTIDO1
SCHEMBL23401352 0.85 CNR2 (0.40) ALDH1A1MAPTRAB9ASMN1; SMN2LMNA
SCHEMBL23400629 0.85 GABRA1 (0.36) GABRA1GABRB2SRCICMTIDO1
SCHEMBL23399593 0.85 ALDH1A1 (0.39) GABRA1GABRB2SRCICMTALDH1A1
SCHEMBL23399288 0.85 MAPK14 (0.36) GABRA1GABRB2SRCICMTRIPK2
SCHEMBL23401020 0.84 RIPK2 (0.39) GABRA1GABRB2SRCICMTRIPK2
SCHEMBL23401249 0.84 KMT2A (0.37) GABRA1GABRB2SRCICMTIDO1
SCHEMBL23402561 0.84 NPC1 (0.41) GABRA1GABRB2IDO1RIPK2MAPK14
SCHEMBL23399916 0.83 RIPK2 (0.36) GABRA1GABRB2SRCICMTRIPK2
SCHEMBL23403146 0.82 RAB9A (0.39) GABRA1GABRB2ALDH1A1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed