SCHEMBL23401439

SCHEMBL23401439

Cc1nn(CC(C)C)c(-c2ccccc2)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CNR2 P34972 2/20 0.40
TRPV1 Q8NER1 3/20 0.38
CNR1 P21554 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
S1PR1 P21453 1/20 0.36
SLC16A3 O15427 1/20 0.36
SLC16A1 P53985 1/20 0.36
PGR P06401 1/20 0.35
NR3C2 P08235 1/20 0.35
AR P10275 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23402795 0.87 PGR (0.38) ALDH1A1SMN1; SMN2CNR2CYP2C19PGR
SCHEMBL23400395 0.85 NPC1 (0.39) ALDH1A1SMN1; SMN2GAASLC16A3SLC16A1
SCHEMBL23398456 0.84 CNR2 (0.40) ALDH1A1SMN1; SMN2CNR2TRPV1CNR1
SCHEMBL23401641 0.83 TRPV1 (0.39) ALDH1A1SMN1; SMN2CNR2TRPV1CNR1
SCHEMBL23400344 0.83 PIK3CD (0.34) ALDH1A1SMN1; SMN2L3MBTL1MAPTTSHR
SCHEMBL23399457 0.83 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2CNR2TRPV1CNR1
SCHEMBL23402208 0.81 HTR2A (0.48) ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL23402499 0.81 CNR2 (0.39) ALDH1A1SMN1; SMN2CNR2TRPV1CNR1
SCHEMBL23400675 0.81 CNR2 (0.39) ALDH1A1SMN1; SMN2CNR2TRPV1CNR1
SCHEMBL23401771 0.81 RAB9A (0.44) ALDH1A1SMN1; SMN2CNR2TRPV1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed