SCHEMBL23401667

SCHEMBL23401667

COc1ccccc1-n1c(=O)c(N)c(-c2ccccc2)n1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.42
PTGS2 P35354 1/20 0.42
MGLL Q99685 1/20 0.41
METAP2 P50579 1/20 0.41
HTR1A P08908 4/20 0.40
ADORA3 P0DMS8 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
UGCG Q16739 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ADRA1D P25100 1/20 0.37
ADRA1A P35348 1/20 0.37
ADRA1B P35368 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23399620 0.83 PTGS2 (0.55) BCHEPTGS2MGLLMETAP2HTR1A
SCHEMBL23402427 0.82 BCHE (0.49) BCHEPTGS2MGLLADORA3LMNA
SCHEMBL23402967 0.81 BCHE (0.51) BCHEPTGS2MGLLADORA3LMNA
SCHEMBL23400524 0.81 PTGS2 (0.55) BCHEPTGS2MGLLMETAP2HTR1A
SCHEMBL23401802 0.81 ALDH1A1 (0.44) BCHEPTGS2ADORA3ADORA2AADORA1
SCHEMBL23399967 0.80 L3MBTL1 (0.43) BCHEPTGS2MGLLMETAP2HTR1A
SCHEMBL23402780 0.80 ALDH1A1 (0.43) BCHEPTGS2MGLLMETAP2HTR1A
SCHEMBL23403344 0.79 ALDH1A1 (0.40) MGLLMETAP2HTR1ALMNATP53
SCHEMBL23402782 0.79 KMT2A (0.47) HTR1ALMNAALDH1A1ADRA1DADRA1A
SCHEMBL23402523 0.76 BCHE (0.51) BCHEPTGS2NPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed