Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 6/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23401724 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL23400704 | 0.87 | MEN1 (0.49) | SMN1; SMN2KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL23402684 | 0.85 | ALDH1A1 (0.46) | SMN1; SMN2KDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL23400166 | 0.83 | TLR8 (0.44) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19710682 | 0.81 | GAA (0.44) | SMN1; SMN2KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL23398865 | 0.79 | MEN1 (0.46) | SMN1; SMN2KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL8892611 | 0.78 | ESRRA (0.53) | SMN1; SMN2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL23400340 | 0.76 | NR1H3 (0.50) | SMN1; SMN2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL23398927 | 0.75 | RAB9A (0.42) | SMN1; SMN2MEN1KMT2AMAPTTDP1 | |
| SCHEMBL23402054 | 0.75 | TLR8 (0.48) | SMN1; SMN2KDM4EALDH1A1L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |