Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101951 | 0.92 | KMT2A (0.51) | KMT2AALDH1A1PTK2BPTGER1MEN1 | |
| Orziloben SCHEMBL6531935 | 0.90 | MEN1 (0.57) | KMT2AMEN1KDM4ERECQLNR1I2 | |
| SCHEMBL23748668 | 0.89 | MEN1 (0.60) | KMT2AMEN1NR1I2LMNACHRM2 | |
| SCHEMBL20503229 | 0.89 | MEN1 (0.60) | KMT2AMEN1NR1I2LMNACHRM2 | |
| Orziloben SCHEMBL23748623 | 0.89 | MEN1 (0.56) | KMT2AMEN1NR1I2LMNACHRM2 | |
| Orziloben SCHEMBL23748710 | 0.89 | MEN1 (0.56) | KMT2AMEN1NR1I2LMNACHRM2 | |
| Orziloben SCHEMBL28616001 | 0.89 | MEN1 (0.56) | KMT2AMEN1NR1I2LMNACHRM2 | |
| SCHEMBL25289272 | 0.88 | ALDH1A1 (0.53) | KMT2AALDH1A1PTK2BPTGER1MEN1 | |
| SCHEMBL11418287 | 0.87 | ALDH1A1 (0.51) | KMT2AALDH1A1PTK2BPTGER1KDM4E | |
| SCHEMBL2345074 | 0.86 | PTGER1 (0.52) | KMT2APTGER1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569195-B2 | Internal and external donor compounds for olefin polymerization catalysts II | BASF CORPORATION (US) | 2013-10-29 | — | — | US | claimed |
| US-20110207901-A1 | INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II | BASF CATALYSTS LLC (US) | 2011-08-25 | — | — | US | claimed |
| EP-3118226-A1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF Corporation (US) | 2017-01-18 | — | — | EP | disclosed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | disclosed |
| EP-2782938-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF Corporation (US) | 2014-10-01 | — | — | EP | disclosed |
| US-8569195-B2 | Internal and external donor compounds for olefin polymerization catalysts II | BASF CORPORATION (US) | 2013-10-29 | — | — | US | disclosed |
| WO-2013077837-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF CORPORATION (US) | 2013-05-30 | — | — | WO | disclosed |
| US-8227370-B2 | High activity catalyst component for olefin polymerization and method of using the same | BASF CORPORATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-20120116031-A1 | High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same | BASF CORPORATION (US) | 2012-05-10 | — | — | US | disclosed |
| US-20110207901-A1 | INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II | BASF CATALYSTS LLC (US) | 2011-08-25 | — | — | US | disclosed |