Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Orziloben SCHEMBL6531935 | 0.95 | MEN1 (0.57) | KMT2AMEN1KDM4ERECQLNR1I2 | |
| Orziloben SCHEMBL23748710 | 0.94 | MEN1 (0.56) | KMT2AMEN1NR1I2LMNACHRM2 | |
| SCHEMBL20503229 | 0.94 | MEN1 (0.60) | KMT2AMEN1NR1I2LMNACHRM2 | |
| SCHEMBL23748668 | 0.94 | MEN1 (0.60) | KMT2AMEN1NR1I2LMNACHRM2 | |
| Orziloben SCHEMBL23748623 | 0.94 | MEN1 (0.56) | KMT2AMEN1NR1I2LMNACHRM2 | |
| Orziloben SCHEMBL28616001 | 0.94 | MEN1 (0.56) | KMT2AMEN1NR1I2LMNACHRM2 | |
| SCHEMBL2340348 | 0.92 | KMT2A (0.51) | KMT2AMEN1KDM4ERECQLNR1I2 | |
| SCHEMBL25289272 | 0.90 | ALDH1A1 (0.53) | KMT2AMEN1NR1I2LMNACHRM2 | |
| SCHEMBL11418287 | 0.85 | ALDH1A1 (0.51) | KMT2AKDM4ELMNAALDH1A1PTK2B | |
| SCHEMBL2345074 | 0.85 | PTGER1 (0.52) | KMT2AMEN1LMNAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53021148-A | — | — | None | — | — | JP | disclosed |
| US-12473249-B2 | Aromatic compounds and pharmaceutical uses thereof | BASF AS (NO) | 2025-11-18 | — | — | US | disclosed |
| US-20210380521-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-12-09 | — | — | US | disclosed |
| US-20210380521-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-12-09 | — | — | US | disclosed |
| EP-3864001-A1 | ROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-08-18 | — | — | EP | disclosed |
| CN-113166024-A | Aromatic compounds and their medical use | 巴斯夫股份公司 | 2021-07-23 | — | — | CN | disclosed |
| US-8501771-B2 | Aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments | SANOFI (FR) | 2013-08-06 | — | — | US | disclosed |
| US-20090082391-A1 | NOVEL AMINOALCOHOL-SUBSTITUTED ARYLDIHYDROISOQUINOLINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SANOFI-AVENTIS (FR) | 2009-03-26 | — | — | US | disclosed |
| JP-S5321148-A | STABLE CHOLESTERIC COMPOUND | CHISSO CORP | 1978-02-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473249-B2 | Aromatic compounds and pharmaceutical uses thereof | GLS2, FFAR3, SLC10A1 | KMT2A 2026/4885MEN1 2226/4885KDM4E 1204/4885 |
| US-20090082391-A1 | NOVEL AMINOALCOHOL-SUBSTITUTED ARYLDIHYDROISOQUINOLINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | MCHR1, AHR, MCHR2 | KMT2A 678/4885MEN1 3044/4885KDM4E 889/4885 |
| US-20210380521-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | GLS2, FFAR3, SLC10A1 | KMT2A 2026/4885MEN1 2226/4885KDM4E 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.